nsatmi on Twitter: "肝代謝のみで消失する薬物の経口投与で、AUCが2倍に上昇する場合。（消化管からの吸収率100%、well- stirred modelに従う） ・肝クリアランスが1/2になる さらに ・非結合形分率が1/2になる ・肝固有クリアランスが1/2になる ＊肝固有クリアランス ...
Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data - ScienceDirect
Example of a scientific poster
The "Well-stirred" Model of Hepatic Clearance - YouTube
演習問題 問54 | 薬がみえるvol.4
ゴロ】well-stirredモデル | ゴロナビ〜薬剤師国家試験に勝つ〜
Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data - ScienceDirect
Quantitative Pharmacokinetics - ppt download
Prediction of Human Hepatic Clearance from in Vivo Animal Experiments and in Vitro Metabolic Studies with Liver Microsomes from Animals and Humans | Drug Metabolism & Disposition
Solved Differential equations Consider the well-stirred tank | Chegg.com
Discussions on the hepatic well‐stirred model: Re‐derivation from the dispersion model and re‐analysis of the lidocaine data | Semantic Scholar
Discussions on the hepatic well‐stirred model: Re‐derivation from the dispersion model and re‐analysis of the lidocaine data | Semantic Scholar
Interpretation of Non-Clinical Data for Prediction of Human Pharmacokinetic Parameters: In Vitro-In Vivo Extrapolation and Allom
Solved 2. Develop a well-stirred reactor model to study the | Chegg.com
An integrated approach to model hepatic drug clearance - ScienceDirect
Discussions on the hepatic well‐stirred model: Re‐derivation from the dispersion model and re‐analysis of the lidocaine data | Semantic Scholar
nsatmi on Twitter: "well-stirredモデルによる分類整理 肝血流律速にしても、肝代謝能律速にしても、AUCに影響を与える因子は、やっぱり ・非結合形分率 ・肝固有クリアランス 肝血流の変動は、吸収↓と消失↓で相殺されるため、AUCに関与しません。 https://t.co ...
Lectures Wednesday, October 8th Monday, October 13th - ppt download
97回薬剤師国家試験 問173解説 | 薬学、これでOK！
Hepatic clearance concepts and misconceptions: Why the well-stirred model is still used even though it is not physiologic reality? - ScienceDirect
Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data - ScienceDirect
Discussions on the hepatic well‐stirred model: Re‐derivation from the dispersion model and re‐analysis of the lidocaine data | Semantic Scholar
Schematic representation of the physiological population PK model for... | Download Scientific Diagram
Are There Any Experimental Perfusion Data that Preferentially Support the Dispersion and Parallel-Tube Models over the Well-Stirred Model of Organ Elimination? | Drug Metabolism & Disposition
In vitro–in vivo extrapolation (IVIVE) for predicting human intestinal absorption and first-pass elimination of drugs: princip
Discussions on the hepatic well-stirred model: Re-derivation from the dispersion model and re-analysis of the lidocaine data - ScienceDirect
